James Cook rushed 17 times for 116 yards and one touchdown in the Bills’ Week 12 loss to the Texans, adding three receptions for 13 additional yards.

21 November 2025

Cook had a solid day on the ground that was buoyed by a 45-yard touchdown run on the Bills’ opening drive. The speedster carefully navigated through the line before breaking into and then past the Texans’ secondary nearly untouched on the way to his eighth rushing touchdown of the season. It was the sixth 100-plus yard performance of the season for Cook, who has now topped 1,000 rushing yards for the third straight year and is on pace to surpass his career-high of 1,122 yards as early as next week. The Bills’ bell cow will be firmly on the RB1 radar in Week 13’s game against the Steelers.