Ricky Pearsall (knee) will not play in Week 5 against the Rams.

01 October 2025

Jauan Jennings was also ruled out. Pearsall is dealing with a nagging knee injury that flared up in his Week 4 matchup with the Jags. Per Kyle Shanahan, he felt “instability” in his knee after the game. Pearsall hasn’t practiced since. Kendrick Bourne and Demarcus Robinson are now the team’s top receivers. Christian McCaffrey will look to set the record for targets by a running back tomorrow. Bourne is familiar with the Shanahan system and was already playing a part-time role before this week. He can be started as a WR5 for fantasy purposes, while Robinson and any other 49ers wideouts are best left on the bench.