49ers QB Brock Purdy (toe) did not practice Tuesday.

30 September 2025

Most importantly, when asked about Purdy, Shanahan said he’d play “if we feel he can play up to 100 percent of his ability.” Purdy looked shaky and was sailing some balls against the Jaguars in Week 4’s return. Mac Jones could be in line for another start against the Rams in Week 5. We already learned that Purdy would be questionable earlier this morning from John Lynch, but this is a discouraging sign for his chances of being active.